ABSTRACT

Introduction The term “peripheral arterial disease” (PAD) covers a multitude of disorders involving arterial beds exclusive of the coronary arteries. There are numerous pathophysiologic processes that could contribute to the creation of stenoses or aneurysms of the noncoronary arterial circulation. Atherosclerosis represents the leading disease process affecting the aorta and its branch arteries. Patients undergoing percutaneous coronary intervention (PCI) who have PAD have been shown to have worse short-and long-term outcomes compared to patients without PAD (1-3). This chapter will cover pharmacotherapy and nonpharmacologic therapies for PAD involving lower extremities.