ABSTRACT
Before we begin our matrix approach to modelling, it is worthwhile re-examining the approach we have used so far. This is best illustrated with the following simple example.
Q: Determine the time dependence of the concentrations of reactants in the two-reaction sequence,
[4.1]S 1 F v1
where v1 and v2 are described by simple reversible Michaelis-Menten rate equations (Section 2.3.3) with all Vmax values being 1 mmol L-1 h-1 and all Km values being 1 mmol L-1 . Suppose that the initial concentrations are S1 [0] = 1 mmol L-1 , S2 [0] = 0, and S3 [0] = 0.