ABSTRACT

Basic CPM approaches work surprisingly well in modeling a wide range of biological processes. In particular, they can provide important new insights into the principles of multicellular (tissutal) patterning in a number of phenomena, as they are able to analyze their driving mechanisms; see, for example, [183, 252, 314]. Moreover, CPM applications are a way of comparing the outcomes of different and equally plausible scenarios, providing a predictive value as well. It is possible in fact to analyze the system’s response to a range of experimental perturbations, as shown in [246, 262, 351, 365].