ABSTRACT

Cell communication in the brain is dynamic, including electrical and chemical components. These dynamics are utilized for maintenance of the highly complex communication pathways within and between cells of the brain, both in health and disease. Bionanocomposites allow us to study brain cell function conceptually from 0 to 3 dimensions (03D), with 0D representing the single cell, 1D representing a linear arrangement of two or more connected cells, 2D including cellular surface areas in both X-and Y-dimensions, and 3D taking into consideration tissue scaffolds that include X-, Y-, and Z-dimensions. These considerations are shown conceptually in Figure 1.