ABSTRACT
Introduction Functional magnetic resonance imaging (fMRI) serves to determine the brain activity during perception or cognition. BOLD contrast for fMRI is remarkable in cognitive neuroscience, surgical treatment planning, and preclinical studies in examining the main parameters such as the blood ow, blood volume, resting state connectivity, and anatomical connectivity within the brain [1]. To dene the cause of the detected activity, the anatomy of the underlying tissue must be analyzed. e functional properties of the region of interests (ROIs) in the brain can be investigated by combination of dierent modalities such as diusion tensor magnetic resonance imaging (DTMRI or DTI), ADC fMRI, and BOLD fMRI [2]. As a noninvasive imaging modality DTMRI helps identication and visualization of the ber connections in the anatomy [3-5]. DTMRI is unique in its ability providing in-vivo anatomical information noninvasively. e potential of DTI is to make the determination of anatomical connectivity in the investigated brain regions by mapping the axonal pathways in white matter noninvasively [6].
