ABSTRACT

Introduction Nanotechnologies are materials and devices that have a functional organization in at least one dimension on the nanometer (one billionth of a meter) scale, ranging from a few to about 100 nanometers. Nanoengineered materials and devices aimed at biologic applications and medicine in general, and neuroscience in particular, are designed fundamentally to interface and interact with cells and their tissues at the molecular level. e potential of nanotechnological applications to biology and medicine arise from the fact that they exhibit bulk mesoscale and macroscale chemical and/or physical properties that are unique to the engineered material or device and not necessarily possessed by the molecules alone. is supports the development of nanotechnologies that can potentially carry out multiple specic functions at once or in a predened sequence, which is an important property for the clinically successful delivery of drugs and other molecules to the central nervous system (CNS).