ABSTRACT
Introduction Imagine trying to nd a familiar face as you walk into a crowded party. As you scan the room, you recognize your friend fairly easily even though she may not be looking directly at you. When you nally make your way towards her and engage in a conversation, she may turn away for a second. Even though the act of your friend turning results in dierent retinal input, you are not led to believe that you are now speaking to a dierent person. Similarly, at this same party, you may put your glass down on a table, and despite looking at it from a dierent angle when you pick it up, you still recognize it as your glass. is success in recognizing people and objects from dierent viewpoints relies on robust image representations that are resilient to large changes in retinal inputs. How one derives these invariant representations is one of the crucial questions in vision science. Despite the large amount of research in this eld, the question of whether or not the strength of these representations changes during our lifetime, or is aected by neurodegenerative disorders like Alzheimer’s disease (AD), has been largely unstudied.
