ABSTRACT

CONTENTS Introduction ................................................................................................................ 45 Methods...................................................................................................................... 47 Subject Recruitment .......................................................................................... 47 Dust Sample Collection and Analysis ............................................................... 47 Serum Hormones ............................................................................................... 48 Semen Quality ................................................................................................... 49 Statistical Analysis ............................................................................................. 49 Results ........................................................................................................................ 50 Discussion .................................................................................................................. 56 Conclusion ................................................................................................................. 58 Keywords ................................................................................................................... 58 References .................................................................................................................. 58 Credits ........................................................................................................................ 61

INTRODUCTION

Organophosphate (OP) compounds, such as tris(1, 3-dichloro-2-propyl) phosphate (TDCPP) and triphenyl phosphate (TPP), are commonly used as additive flame-retardants and plasticizers in a wide range of materials. Although widespread human exposure to OP flame-retardants is likely, there is a lack of human and animal data on potential health effects.