ABSTRACT
The method by which a drug is delivered can have a significant effect on its efficiency. Therefore, the design and development of advanced drug delivery systems has emerged last four decades in order to improve their biocompatibility (Kocsis et al., 2000), controlled release (Gibbs et al., 1999; Uhrich et al., 1999), active targeting in tissues (Vasir et al., 2005; Yokoyama, 2005), and stimuli response (MacEwan et al., 2010). The strategy used to develop smart drug cargos is based on interdisciplinary approaches that combine polymer science, pharmaceutics and molecular biology.
