ABSTRACT
Brain hypoxia is widespread in clinical picture of neuropsychic deceases and is a typical post-resuscitation complication. Effects of the hypoxia include diffuse degeneration and death of the neurons, leading to learning, and memory disturbances (Boksa et al., 1995; Hymel et al., 2007; Jellinger, 2008; Voronina, 2000). Hypoxic hypoxia (HH) is one of the well studied animal (rat) models of diffuse brain degeneration. Therefore, HH is a very suitable model for study of similar deceases (Polezhaev and Aleksandrova, 1983). Neurotransplantation of few differentiated brain tissues contained stem cells is a new and promising strategy for treatment of neurogenerative diseases, including brain hypoxia (Aleksandrova, 2001; Loseva, 2001; Polezhaev and Aleksandrova, 1983; Polezhaev et al., 1993). The ability of stem cells to express wide spectrum of active molecules (growth factors, neurotrophic factors, cytokines etc.) underlies their action. These active molecules are per se the natural nanostructures that are necessary for activation of reparative processes in damaged brain (Bath and Lee, 2010).
