ABSTRACT
Genetic toxicology addresses the identi•cation, analysis, and management of agents with toxicity directed toward the hereditary components of living organisms. A large
proportion of human disease is either directly or indirectly associated with altered genetic information. Although many agents are capable of indirectly altering DNA functionality at excessively high exposure concentrations, the primary objective of genetic toxicology is to identify and assess genetic
Introduction ..............................................................................................................................................................................1173 Basic Genetic Concepts ...........................................................................................................................................................1174
