ABSTRACT

Although technology is sufciently sensitive to provide extensive genomic and metabolomic data within a short time frame, little research involving nutrition in the form of dietary intervention studies has been used to stratify the population with respect to benet. For a small number of products or ingredients, sufcient information is available; personalized nutrition in a broad sense is not yet ready for the consumer [4]. However, there are specic diseases that have been well characterized [5,6], and certain foods or food groups [7] that can be personalized. The severity of disease and the ability to prevent or ameliorate its impact through nutrition and other lifestyle factors, together

25.1 Introduction ........................................................................................................................ 371 25.2 Nutrigenetic Approaches to Personalizing Nutrition .......................................................... 372 25.3 Selenium Studies ................................................................................................................ 372

25.3.1 Integrating Genetic and Diet Information with Other Genomic Technologies .... 374 25.4 The Gut Microora Add Another Dimension .................................................................... 374 25.5 Public Acceptance of Personalized Nutrition ..................................................................... 375

25.5.1 Functional Foods .................................................................................................. 376 25.5.2 Possible Harm ....................................................................................................... 377 25.5.3 Effect of Testing and Carrier Status on Perceived Risk and Motivation .............. 377 25.5.4 Inuence of Existing Levels of Motivation on Willingness

to Modify Behavior ............................................................................................ 377 25.5.5 Inuence of Existing Health Problems on Attitude to Testing ............................. 377 25.5.6 Potential for Stigmatization .................................................................................. 377 25.5.7 Privacy and Trust .................................................................................................. 378

25.6 Concluding Comments ....................................................................................................... 378 References ...................................................................................................................................... 378

with acceptance of personalized nutrition by the general public, will contribute toward determining the impact on public health.