ABSTRACT

An accruing body of research in a range of healthy and diseased populations has begun to show that nutrition can have an effect on cognitive function. The detection of a relationship between nutrition and cognitive health requires careful selection of cognitive assessments to identify participants for enrolment into studies of potential treatments and to monitor and detect subtle or more overt changes in cognition as a result of intervention. A plethora of cognitive instruments are available to measure cognition, but not all will be most efcient for the task at hand. The decision to include tests into a battery will be based on a number of considerations. This

Summary .................................................................................................................. 75 4.1 Methodology: Key Considerations in the Psychometric Properties of

Cognitive Tests ................................................................................................ 76 4.1.1 Sensitivity and Specicity .................................................................. 76 4.1.2 Impairment Criteria ............................................................................ 76 4.1.3 Reliability and Validity ....................................................................... 78 4.1.4 Normative Data ................................................................................... 79

4.2 Cautions in Assessing Cognitive Function .....................................................80 4.2.1 Practice Effects ...................................................................................80 4.2.2 Participant Characteristics ..................................................................80