ABSTRACT

In the acute clinical setting both computed tomography (CT) and conventional magnetic resonance imaging (MRI) are established imaging modalities to rule out severe complications resulting from traumatic brain injury (TBI) such as skull fracture, intracranial hemorrhage, and brain edema. However, when applied to mild traumatic brain injury (mTBI) only about 10% of CT scans and 30% of MR scans reveal abnormalities such as subdural or subarachnoidal hemorrhage.1-3 Moreover, conventional CT and MRI have proven insensitive to more subtle changes in the brain such as

Introduction to Neuroimaging of Mild Traumatic Brain Injury ............................. 277 High-Resolution Structural Magnetic Resonance Imaging ................................... 278 Susceptibility-Weighted Imaging ........................................................................... 279 Functional Magnetic Resonance Imaging (fMRI) and Resting State Functional Magnetic Resonance Imaging (rsfMRI) .............................................. 281 Dynamic Susceptibility Contrast MRI ................................................................... 282 Arterial Spin Labeling ............................................................................................ 282 Diffusion Tensor Imaging ...................................................................................... 283

Future Directions of DTI ...................................................................................285 Technical Improvements of DTI ..................................................................285 Novel Tools ...................................................................................................285 A Focus on Individual Profiles of Injury ......................................................286