ABSTRACT
Malignant hyperthermia is an inherited disorder of skeletal muscle that can be pharmacologically triggered to produce a combination of hypermetabolism, muscle rigidity and muscle breakdown. The incidence of reported malignant hyperthermia reactions varies from 1:40000 to 1:100000 anaesthetics. Estimates of the population prevalence of the genetic susceptibility are between 1:5000 and 1:10000.
