ABSTRACT

The treatment of childhood cancer has become increasingly successful over the last forty years, and during the last two decades in particular, and the overall cure rate is now 60-70%. This, in turn, has introduced new issues for the clinician as the number of long-term survivors has increased. Some of the therapies that have contributed most to the

chapter |1 pages

REFERENCES

chapter 2|2 pages

Neurological and special senses

chapter |1 pages

PATRICIA K DUFFNER

Long-term neurologic consequences of CNS therapy

chapter |9 pages

Thalidomide neuropathy

chapter |3 pages

REFERENCES

chapter |9 pages

RAYMOND K MULHERN, SEAN PHIPPS AND HOLLY WHITE

Neuropsychological outcomes

chapter |4 pages

Retina

chapter |4 pages

PATRICIA D SHEARER

Hearing impairment

chapter |2 pages

REFERENCES

chapter 3|2 pages

Secondary primary cancers

chapter |1 pages

SMITA BHATIA

Epidemiology

chapter |3 pages

KEY POINTS

chapter |17 pages

MANUEL DIEZI AND DAVID MALKIN

Genetic susceptibility and familial cancer syndromes

chapter 4|2 pages

Cardiovascular complications

chapter |5 pages

Diet

chapter |13 pages

GILL A LEVITT AND FRANK H SARAN

Radiation damage

chapter 6|2 pages

Urological complications

chapter |4 pages

RODERICK SKINNER

Renal damage

chapter |4 pages

Clinical management

chapter |5 pages

Prevention

NEPHROTOXICITY DUE TO OTHER

chapter |2 pages

Chemotherapy

chapter |1 pages

Augmentation cystoplasty

chapter |9 pages

JOHN W GREGORY AND JOHN J REILLY

Body composition and obesity

chapter |6 pages

BOYS 0–20 yrs

chapter |8 pages

NIGEL MEADOWS

The late effects of pediatric cancer treatment on the gastrointestinal tract

chapter |6 pages

MELISSA M HUDSON

Hepatic complications

chapter |11 pages

ANDREW L SONIS

Craniofacial development, teeth and salivary glands

chapter 8|2 pages

Endocrine and fertility effects

chapter |8 pages

KEN H DARZY, HELENA K GLEESON AND STEPHEN M SHALET

Growth and neuroendocrine consequences

chapter |1 pages

THYROID-STIMULATING HORMONE DEFICIENCY

chapter |7 pages

GROWTH AND CANCER TREATMENT

chapter |1 pages

HELEN A SPOUDEAS

Disturbance of the hypothalamic–pituitary thyroid axis

chapter |5 pages

Thyrotrophin secretion

chapter |4 pages

Hypothyroidism

chapter |3 pages

REFERENCES

chapter |4 pages

HILARY OD CRITCHLEY, ANGELA B THOMSON AND W HAMISH B WALLACE

Ovarian and uterine function and reproductive potential

chapter |10 pages

INVESTIGATION OF UTERINE FUNCTION

chapter |14 pages

TESTICULAR DAMAGE

chapter |8 pages

DANIEL M GREEN

Pregnancy outcome

chapter |2 pages

KEY POINTS

chapter 9|2 pages

Musculoskeletal complications

chapter |1 pages

BERNADETTE MD BRENNAN

Osteoporosis

chapter |7 pages

Growth hormone deficiency

chapter |11 pages

PATRICIA M CROFTON

Bone and collagen turnover

chapter |3 pages

REFERENCES

chapter |1 pages

HANNAH MORGAN AND ERNEST U CONRAD III

Limb salvage and spinal surgery

chapter |2 pages

LIMB-SALVAGE TECHNIQUES

chapter |7 pages

Leg-lengthening techniques

chapter |7 pages

Dermatological

chapter |4 pages

Molluscum contagiosum

chapter 12|2 pages

Quality of life issues

chapter |15 pages

CHRISTINE EISER

Quality of life and body image

chapter |3 pages

GRACE-ANN P MONACO AND GILBERT SMITH

Legal issues: US perspective

chapter |2 pages

• • •

chapter |1 pages

CONCLUSION

chapter |1 pages

ALEXANDER MCALL SMITH

Legal issues: UK perspective

chapter |8 pages

CONFRONTING DISCRIMINATION

chapter |5 pages

Tobacco

chapter 14|2 pages

Strategy for long-term follow up

chapter |10 pages

KEVIN C OEFFINGER

US perspective

chapter |3 pages

KEY POINTS

Screening asymptomatic survivors