chapter
Introduction
Pages 4

Antibiotics Penicillins Penicillins are rapidly eliminated, particularly by glomerular filtration and renal tubular secretion. With some (e.g. cloxacillin), metabolic transformation occurs, especially in anuric patients. When renal function is impaired, 7-10% of the antibiotic will be inactivated by the liver per hour. Adverse drug reactions are: