ABSTRACT
Niosomes, which are the self-assembly of nonionic amphiphiles, are closed bilayer vesicles ranging in size from microns to nanometers. Niosomes are attractive because of their structural similarity to liposomes and their alternative application potential in the cosmetic and pharmaceutical industries. Analogous to liposomes, niosomes show great advantages in stability, cost, and safety. The mechanism of nonionic surfactant vesicle formation in aqueous media involves their amphiphilic nature and helper additives like cholesterols, which were well reviewed by Uchegbu and Vyas (1998).
