ABSTRACT
Our current understanding of ocular anatomy and physiology has impeded the development of a truly effective noninvasive method to deliver drugs to the posterior segment. The drug delivery platforms such as drops, inserts, and injections that are currently used in the patient care setting are each effective and safe for a limited number of drug entities; however, a gold standard method that is well tolerated,
11.1 Introduction .................................................................................................. 215 11.1.1 Basic Needs of Ocular Drug Delivery .............................................. 215 11.1.2 Continued Need for Improvement .................................................... 216
11.2 Methods of Approaching Scleral Delivery ................................................... 217 11.2.1 Juxta-Scleral Delivery ...................................................................... 218 11.2.2 Episcleral Delivery ........................................................................... 218 11.2.3 Intrascleral Delivery ......................................................................... 218 11.2.4 Transscleral Delivery ........................................................................ 219
11.2.4.1 Iontophoresis ...................................................................... 219 11.2.4.2 Photokinetic Drug Delivery ...............................................220
