ABSTRACT
While melatonin was initially discovered by Lerner et al. [1] as a hormone produced by the pineal gland that lightens frog skin, the discovery of its strong antioxidative properties by Tan et al. [2] opened a wide £eld of research activities and applications of melatonin in a great variety of physiology and pathophysiology conditions in universal biology-from unicellular organisms, to animals, and to human being [3-11].
