ABSTRACT

Appropriations Process ................................................................................... 13 2.4 Medical Research Produces the Intellectual Capital Infrastructure for

Healthcare ....................................................................................................... 14 2.5 Aligning Payments for Medical Research with Bene–t Groups..................... 14 2.6 Cost of Transformative Long-Term Research Should Be Spread over

Bene–tting Generations .................................................................................. 15 2.7 Empowering a New Political and Funding Paradigm for Medical Research .... 15 2.8 Creating State Paradigm to Complement Federal Research Funding ............ 17

2.8.1 California Model ................................................................................ 18 2.9 Basic Rationale of California Model .............................................................. 21 2.10 Optimizing Governmental Cash Flow of California Research Funding

Model .............................................................................................................. 21 2.11 Models Providing Enhanced Opportunities ...................................................23 2.12 Relationship of Research Complexity to Capital ............................................24 2.13 Interface of Governmental Funding with Private Capital Markets ................26 2.14 California Model for Funding Large-Scale Biotech Research .......................26