ABSTRACT
The process of solubility is as follows. The solute (for example, NaCl) is added to water. NaCl dissociates into Na+ and Cl-ions. These ions are surrounded by water molecules. Ions are known to interact through dipoles and hydrogen bonds with water molecules. On the other hand, when a water-insoluble-organic molecule is placed in water, this system is found to be different than in the case of NaCl or other similar electrolytes. The organic molecule will not interact with dipoles of surrounding water molecules. The solubility of such organic molecules thus requires a cavity in water. It is also essential to visualize that the bigger the cavity needed, the lower is the solubility in water (since cavity requires energy).
