ABSTRACT
The experimental methods described in Table 17.1 relate mainly to animal models of diabetes in rats and mice. One classical way of inducing diabetes in rodents is with alloxan, a drug causing destruction of cells of the pancreatic islets of Langerhans, or with the alkylating agent used for metastatic islet cell cancers, which produces the same effect as alloxan. Both methods can be understood as producing models for type 1 disease.
