ABSTRACT
Diabetes represents one of the primary health concerns of the twenty-rst century. However, the most common method of glucose level monitoring (e.g., nger-stick method) can be as problematic as the disease itself, as diabetics are required to obtain blood samples up to ve times per day. This procedure is painful and inconvenient, and as a result patients tend to test themselves less frequently, which translates to less effective glycemic control. This situation has been described by experts in the eld as comparable to a “glycemic” roller coaster ride that diabetes patients must endure on a daily basis, blindfolded. Each nger stick provides only an isolated snapshot of the blood glucose value in real time, devoid of any information in regard to how low or high the level will fall or rise over the next moments (Figure 10.1). This constitutes a frightening situation indeed, albeit one that has bolstered the many research efforts currently underway, in an attempt to assist with remedying this situation. Noninvasive and continuous glucose monitoring (CGM) comprises one of the most highly investigated areas, which may have great potential to increase patient usage. This strategy may signicantly improve the lives and health of diabetes patients [1-3].
