chapter  9
40 Pages

Recent Developments and Applications in Nonlinear Reversed Phase Liquid Chromatography

Interaction Elution Mechanisms ....................................................... 435 Acknowledgments .................................................................................................. 438 References .............................................................................................................. 438

High performance liquid chromatography is today the most prominent technique for adsorption study. Studying adsorption equilibria and possibly involved secondary equilibria (i.e., competition for adsorption sites other compounds, organic solvent molecules, employed mobile phase additives, or presence of other batch equilibrium) by dynamic approaches can allow deep investigations on unclear separation mechanisms, as well as ˆnding or developing the right models to describe the chromatographic process under a wide range of sample concentrations (nonlinear chromatography). For many years, this has been strictly related to important ˆelds in academic research, analytical chemistry analysis, and industrial processes.