chapter  3
46 Pages

Chromatographic Separation and NMR

Nuclear magnetic resonance (NMR) is a powerful technology that has been extensively used for the structural elucidation and characterization of organic, inorganic, and biological molecules. Sophisticated advances in spectroscopic instrumentation along with advances in multidimensional NMR and solvent suppression techniques have vastly expanded the range and breadth of NMR capabilities. This has been realized particularly with respect to the more challenging issues regarding sensitivity and limits of detection. These advances have had an acute impact on the hyphenated chromatographic-NMR capabilities.