ABSTRACT

Lung cancer is the most common cause of cancer death in the United States for both sexes [1]. Among various types of small cell and non-small cell lung cancers, adenocarcinoma is the most prevalent type, accounting for more than a third of all primary lung tumors, and its incidence has been increasing in the past few decades [2]. X-ray computed tomography (CT) is one of the most sensitive imaging domains for noninvasive diagnostics of adenocarcinomas [3]. The recent advances in three-dimensional (3D) imaging technology, such as high-resolution and multidetector CT, have greatly improved image resolution

CONTENTS

4.1 Introduction: Literature Review ........................................................................................65 4.1.1 Radiographic Characteristics of GGNs .................................................................66 4.1.2 Nomenclature of GGNs ..........................................................................................66 4.1.3 Clinical Prevalence: Epidemiology .......................................................................66 4.1.4 Malignancy of GGNs...............................................................................................66 4.1.5 GGNs’ Evolution and Histopathological Disease Progression ......................... 67 4.1.6 Computer-Aided Detection and Diagnosis of GGNs ......................................... 67 4.1.7 Lung Nodule Volumetry and Its Limitation ........................................................68 4.1.8 GGN Characterization: Our Approach ................................................................68