ABSTRACT
Interaction of HA with receptors such as CD44 and RHAMM on and in keratinocytes can lead to a delay of differentiation or an accelerated cell growth. In this context, some authors suggest that topically applied HA may improve wound healing because it may provide an optimal environment for proliferating fibroblasts (113-115). HA turnover rate in epidermis and dermis is approximately 24 hours (116).
