ABSTRACT

The intracellular concentrations of tocotrienol isomers were higher than those of tocopherol isomers in intestinal epithelial Caco2 cells (Tsuzuki et al., 2007). The concentrations of each of the tocotrienol isomers and those of each of the tocopherol isomers were nearly identical, but the concentrations of the δ-isomers (both tocopherol and tocotrienol) tended to be highest. The authors suggested that the structure of the phytyl chain (saturated or unsaturated) is much more critical for cellular uptake than that of the chromanol ring.