ABSTRACT

The protocol studied by Cotton and colleagues involves the use of two units of plasma per three units of PRBC and one single donor pheresis pack of platelets for every five units of PRBC. (9) Similarly, Duchesne et al. have questioned the last 60 years of resuscitation practices, based on their improved results with increased plasma-based resuscitation.(13) The preponderance of data in this evolving field suggest that increased plasma and platelet use, accompanied by decreased crystalloid use, improves outcome.