ABSTRACT
Pain of renal origin is very frequent in medical practice. Its most typical expression, the renal colic, represents one of the most prominent and paradigmatic forms of visceral pain (1). This type of pain has been the subject of extensive investigation not only in clinical studies but also in basic research studies on animal models, to assess the profile of the sensory and trophic changes that appear in the referred area and investigate their pathophysiological bases (2,3). This chapter is intended to provide an overview of the current knowledge on pain phenomena of renal origin, in terms of clinical characterization, mechanisms of generation, diagnostic tools, and therapeutic approach.
