ABSTRACT
The emergence of the epidemic of the acquired immunodeficiency syndrome (AIDS) resulting from infection with human immunodeficiency virus (HIV) brought the consequences of many uncommon or previously unrecognized secondary infections to the forefront of clinical infectious diseases. This included an expansion of the recognized role of Epstein-Barr virus (EBV) in human disease (see Chapter 9). In addition to its role in oral hairy leukoplakia and lymphoid interstitial pneumonitis, EBV was linked with an increased risk of lymphoma, especially of the central nervous system.
