ABSTRACT
CASRN: 127-19-5; molecular formula: C4H9NO; FW: 87.12; RTECS: AB7700000; Merck Index: 12, 3277 Physical state, color, and odor: Clear, colorless liquid with a weak, ammonia-like odor. Odor threshold concentration is 46.8 ppmv (Leonardos et al., 1969). Melting point (°C): -20 (Weast, 1986) Boiling point (°C): 165.5 (Dean, 1987) Density (g/cm3): 0.9372 at 25.00 °C, 0.9325 at 30.00 °C, 0.9278 at 35.00 °C (Aralaguppi et al., 1997) Diffusivity in water (x 10-5 cm2/sec): 0.89 at 20 °C using method of Hayduk and Laudie (1974) Flash point (°C): 77.2 (open cup, Sax and Lewis, 1987) 70 (NFPA, 1984) Lower explosive limit (%): 1.8 at 100 °C (NFPA, 1984) Upper explosive limit (%): 11.5 at 160 °C (NFPA, 1984) Ionization potential (eV): 8.81 ± 0.03 (Franklin et al., 1969) 8.60 (HNU, 1986) Soil organic carbon/water partition coefficient, log Koc: Unavailable because experimental methods for estimation of this parameter for aliphatic amides are lacking in the documented literature. However, its miscibility in water and low Kow suggest its adsorption to soil will be nominal (Lyman et al., 1982). Octanol/water partition coefficient, log Kow: -0.77 at 25 °C (shake flask-radiochemical method, Wolfenden, 1978) Solubility in organics: Miscible with aromatics, esters, ketones, and ethers (Hawley, 1981)
Miscible (NIOSH, 1997). Vapor pressure (mmHg): 2 at 20 °C (NIOSH, 1997) 1.3 at 25 °C, 9 at 60 °C (quoted, Verschueren, 1983) 49.13 at 125.4 °C (de Haan et al., 1997) Environmental fate: Chemical/Physical. Releases toxic fumes of nitrogen oxides when heated to decomposition (Sax and Lewis, 1987). Exposure limits: NIOSH REL: TWA 10 ppm (35 mg/m3), IDLH 300 ppm; OSHA PEL: TWA 10 ppm; ACGIH TLV: TWA 10 ppm (adopted). Toxicity: LC50 (1-h inhalation) for rats >2,475ppm (Kennedy and Sherman, 1986). Acute oral LD50 for male rats 5,809 mg/kg, female rats 4,930 mg/kg (Kennedy and Sherman, 1986). Uses: Solvent used in organic synthesis, paint removers, plastics, resins, gums, and electrolytes; chemical intermediate; catalyst; extracting agent for gases and oils; purifying and crystallizing aromatic dicarboxylic acids.
