ABSTRACT
Etiology, Pathophysiology, and Pathogenesis ANational Institutes of Health (NIH) consensus panel defined restless legs syndrome (RLS) as: (i) an urge to move the limbs with or without sensations, (ii) worsening at rest, (iii) improving with activity, and (iv) worsening in the evening or night (1). The diagnosis of RLS is exclusively based on these criteria. A validated diagnostic phone interview (2), rating scale (3), and quality of life scale (4) have all been developed based on these features.
