ABSTRACT
I. Introduction ...................................................................................................................... 499
II. Theory and Methods ........................................................................................................ 500
A. Electron Transfer Theory......................................................................................... 500
B. Proton Transfer Theory............................................................................................ 501
C. Proton-Coupled Electron Transfer Theory .............................................................. 502
D. Methodological Developments ................................................................................ 505
III. Applications to Chemical and Biological Systems ......................................................... 506
A. PCET in Solution ..................................................................................................... 506
B. Enzyme Reactions.................................................................................................... 508
C. Role of Motion in Enzyme Reactions ..................................................................... 512
IV. Summary and Conclusions .............................................................................................. 514
Acknowledgments ........................................................................................................................ 515
References..................................................................................................................................... 515
The coupling between proton and electron transfer reactions is vital for a wide range of chemical
and biological processes, including photosynthesis,
respiration,
and numerous enzyme
reactions.
