ABSTRACT
Sequences corresponding to single nucleotide polymorphisms (SNPs) allow for the arraying of SNPs onto high-density chips, and techniques such as comparative genomic hybridization could be translated to an array-based platform to allow for a comprehensive study of genomic changes. Because of the tedious and costly nature of large-scale sequencing projects, many laboratories tend to conduct high-throughput gene expression studies using techniques such as microarray analysis. However, of the sequencing studies that have been conducted, some fundamental observations that have literally refocused the field of melanoma research have emerged. The vast potential of genomic technology to transform the diagnosis of melanocytic neoplasms and the therapy of advanced melanoma is beginning to be felt. In short, the repertoire of genomic therapies currently available provides with a formidable array of tools with which to tackle the problem of recurrent melanoma.
