ABSTRACT

The normal function of the urinary bladder is to store and expel urine in a coordinated, controlled fashion. This coordinated activity is regulated by the central and peripheral nervous systems. Neurogenic bladder is a term applied to a malfunctioning urinary bladder due to neurogenic dysfunction or insult emanating from internal or external trauma or disease. Neurogenic lower urinary tract dysfunction (NLUTD) is the new term currently applied to ‘‘neurogenic bladder dysfunction’’. NLUTD is a multi-facetted pathology and an important clinical as well as public health problem that is associated with complex management issues. Therefore, knowledge of the anatomy and pathophysiology of NLUTD remains the prerequisite for the safe and appropriate surgical-medical management of this disorder.