ABSTRACT

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For the past three decades, sugars and closely related mono-and bicyclic polyhydroxy compounds

with heteroatoms other than oxygen in the ring, together with carbasugars in which the ring oxygen

is replaced by a carbon atom, have accounted for a predominant portion of the carbohydrate

literature not related to glycoside synthesis. This has occurred because of the diverse biological

activities of these sugar mimetics and their eminent importance for carbohydrate chemistry and

biochemistry as we understand it at the beginning of its second century.