ABSTRACT
A syndrome is defined as a constellation of symptoms and signs that collectively characterize an
abnormal condition or disease state, while craniosynostosis is defined as the premature fusion
of the cranial sutures (1). This chapter will focus on the most common group of syndromic
craniosynostoses and describe the salient points in their proper clinical and surgical manage-
ment. As a group, the syndromic craniosynostoses may also be referred to as the craniofacial
dysostosis syndromes. Both terms are often used interchangeably; however, the latter may
better connote the scope of the deformity, which includes the cranial vault and the full extent of
the facial skeleton.
