ABSTRACT

Many patients with signs and symptoms of heart failure have normal or near normal left

ventricular ejection fraction. In 1988, Kessler introduced the term “diastolic heart failure”

to describe these patients (1). More recently, Aurigemma and Gaasch suggested a more

comprehensive definition: “if effort intolerance and dyspnea develop in a patient with

hypertensive left ventricular hypertrophy, normal ejection faction and abnormal left

ventricular filling, especially in combination with venous congestion and pulmonary

edema, it would be appropriate to use the term diastolic heart failure (2).” Alternatively,

Grossman and others have proposed purely pathophysiologic definitions, such as filling of

the left ventricle to a normal end-diastolic volume only at higher than normal pressure (3).