ABSTRACT

Resveratrol, a compound present in grape skins and wine, is thought to be the active principle with antibacterial activity. Resveratrol and p-hydroxybenzoic acid enhanced the antibacterial activities of catechin-gallate and the proanthocyanidins. Chlamydia pneumoniae (CP), an intracellular Gram-negative bacterium, is known as a leading cause of human acute respiratory tract infections worldwide, accounting for 5 to 10% of all cases of pneumonia. In numerous investigations, chronic CP infections have also been implicated as a causative factor in the development of atherosclerosis and coronary artery disease. Helicobacter pylori (HP) is a curved or spiral shaped bacteria located on the gastric epithelium of patients with chronic active gastritis. In 1994 HP was classified as a group I carcinogen and a definite cause of gastric cancer in humans by the International Agency for Research on Cancer. Neisseria is the genus of Gram-negative bacteria responsible for the development of the sexually transmitted disease gonorrhea.