ABSTRACT

I. INTRODUCTION Unfortunately, the treatment of most common solid tumors in adults has not reproduced the encouraging improvements in response and survival demon­ strated with chemotherapeutic intervention in the hematological cancers over the last 20-30 years. Many reasons can be cited for this disappointing state of affairs, but it is clear that for the common solid cancers (lung, colorectal, breast), in their advanced stages, chemotherapy is (at best) only palliative.