Spectral Imaging for the Investigation of the Intracellular Fate of Liposomes

In principle, liposomes can enter (target) cells through different pathways: by direct fusion of liposomes and the plasma membrane (1) or by an endocytic uptake mechanism. Other liposome-cell interactions that have been described in the literature are absorption, phospholipid and protein exchange, and cell-induced leakage of liposome contents (2,3).