ABSTRACT
I. Introduction 225
II. Prevalence 226
III. Underlying (Predisposing) Factors 226
IV. Immune Deficiency 226
IV. Muco-Ciliary Clearance 227
V. Nitric Oxide 228
VI. Atopy 229
VII. Conclusion 230
References 231
I. Introduction
Chronic rhinosinusitis in children is a hotly debated topic (1). Since the natural
history is only partly known, it is difficult to evaluate treatments which range
from complete nonintervention through medical therapy to sinus surgery,
which these days is likely to be endoscopic. A recent consensus report has
encouraged the definition of pediatric rhinosinusitis on clinical grounds,
without the necessity of a computed tomography (CT) scan (1).
