ABSTRACT

The inhibitory amino acids, gamma-aminobutyric acid (GABA) and glycine, play a critical role in the coding of acoustic information in auditory brainstem structures. The cochlear nucleus, superior olivary complex, or nuclei of the lateral lemniscus and inferior colliculus contain numerous extrinsic and intrinsic circuits that utilize GABA and/or glycine in the detection of signals in noise, echo suppression, and the localization of sound in space. This chapter focuses on what is known about GABA and glycine from studies conducted in mouse auditory brainstem.