ABSTRACT

Marlene M. Most, Valerie Fishell, Amy Binkoski, Stacie Coval, Denise Shaffer Taylor, Guixiang Zhao, and Penny Kris-Etherton

Nutrition research is the hallmark of establishing nutrient requirements and giving dietary guidance to promote health and wellbeing throughout life. Over the years it has been an active area of investigation, leading to the discovery of many important findings that have provided the basis for dietary guidelines and recommendations. Until recently, resources describing the design, implementation, and management of clinical nutrition studies were limited. Because of the growing interest and activities in clinical nutrition research, a number of important resources are now available that describe key aspects of conducting clinical nutrition studies. These resources (i.e., books and journal articles) are listed in Table 16.1. They provide detailed information about all aspects of conducting nutrition research with human participants. Collectively, they are a wealth of information for all researchers interested in and actively involved with human nutrition research. Indeed, these resources are a true “goldmine” to the field for standard studies, including those that employ either a single-or multicenter model. However, there are many studies that are uniquely different, presenting what may seem to be insurmountable challenges with respect to the experimental design, diet design, participant population studied, and feeding model utilized. For the most part, these have not been discussed in detail in the publications listed in Table 16.1.