ABSTRACT
I. Introduction ....................................................................................242 A. Historical Perspective of Genotoxicity and
Genetic Ecotoxicology............................................................242 B. Genotoxic Compounds and Agents in the Environment ...243 C. Linking the Mechanism of Genotoxicity with
Its Consequences ....................................................................244 II. The Use of Reptilian Species in the Study of Aquatic and
Terrestrial Genotoxicity.................................................................246 A. Biomarkers of Exposure and Effect in
Reptilian Populations ............................................................249 1. DNA Damage as a Biomarker of Exposure ...............249 2. Neoplasia as a Biomarker of Effect..............................251
III. Reptilian Models for Studies of Genotoxicity...........................252 A. Chelonia ...................................................................................252