ABSTRACT

The three major types are

γ

,

α

, and µ.

γ

-Heavy-Chain Disease (γ

-HCD)

This lymphoplasmacytic cell proliferative disorder produces a monoclonal

γ

-heavy-chain in the serum or urine. The

γ

-chains have significant amino acid deletions. The median age is approximately 60 years, although it has been noted in young persons.