ABSTRACT
The eye is a complex organ with a vast number of different proteins. Each ocular tissue and cell type has distinct protein expression profiles reflecting the function and condition of the cell/tissue. Thus, to better understand the molecular processes of the
eye in health and disease a determination of proteins in the different compartments of the eye is important. In addition, many differentially expressed proteins in ophthalmic diseases are potential targets for therapeutic agents or suggest what processes are distorted in the disease (356). Previously, protein characterization involved only
one or a few proteins at a time. However, recent technological developments now enable the simultaneous analysis of all the proteins in a system and the evaluation of changes in the protein expression as a consequence of disease and external factors.
