ABSTRACT

The beginning of this century brought with it an explosion of knowledge in the field of oncogenesis. Perhaps the most prominent aspect of our collective knowledge of carcinogenesis is its heterogeneous nature in every respect, from the gene mutating events that initiate the process to the histological and clinical presentations. Instead of isolated specific carcinogenic culprits, cancer-related research has uncovered a plethora of different contributing factors leading to its pathogenesis. The explosion of studies in this field has taught us that this is a disease with multiple causes, which will likely require a similar multitude of therapeutic approaches.